Britain will play three Twenty20s and three one-day internationals from 27 November, all in secret.
The group will head out to South Africa on 16 November, with games played at Cape Town’s Newlands and in close by Paarl.
It will be South Africa’s first cricket since the game’s Covid closure and England’s first matches abroad.
The South African government sees the UK as ‘high danger’ for Covid which had placed the visit in question.
The England players and the board have been conceded exceptions to travel.
They will be situated in Cape Town and will prepare at Western Province Cricket Club, playing three intra-crew matches before the main T20.
Britain figured out how to finish their whole timetable of home men’s global cricket this mid year notwithstanding the pandemic by playing matches in bio-secure settings.
They are booked to play Sri Lanka and India from the get-go in 2021 however neither one of the tours has been affirmed.