Miles Morales/Spider-Man Miles Morales was first introduced to audiences in Spider-Man: Into the Spider-Verse. Into the Spider-Verse showed Marvel and Sony that audiences want more Miles Morales. 

Deadpool As soon as filming begins on Deadpool 3, Ryan Reynolds will be ready to go. Wade Wilson may appear in the MCU sooner rather than later after Disney and Fox merge.

Mystique The X-Men franchise has already introduced moviegoers to Mystique. Alternatively, Marvel could use Rebecca Romijn or Jennifer Lawrence to introduce a new Mystique. 

Maestro She-Hulk: Attorney at Law on Disney+ would be an excellent introduction to the other Hulk variants.. 

American Dream Unlike Earth-616, the Marvel Comic Universe as we know it, American Dream comes from Earth-928. 

Iron Punisher Mercenary turned super soldier turned Iron Man, Frank Castle from Earth-28918. 

Gwenom In Earth-65, Gwen Stacy is known as Spider-Gwen, but Peter Parker and Eddie Brock aren't the only ones to have encountered symbiotes.

Sentry Sentry is one of, if not the most overpowered character in Marvel’s line up. 

Angela This one may be a little on the tricky side. After a long dispute, Angela was plucked from Image Comics (where she was created) and given to Marvel Comics (where she currently resides).